The Universidad Autónoma Gabriel René Moreno (Gabriel René Moreno Autonomous University) is a university in Santa Cruz de la Sierra, Bolivia. It was created by the supreme decret of December 15, 1879. The first governor was Bishop Juan Jose Valdivia, and the first university careers offered were Medicine, Theology, and Law.

The University is named after thinker, historian, and literary figure Gabriel René Moreno, called the Prince of the Letters.